Hematological parameters of dogs for parasitism Dirofilaria immitis

The relationship between helminths and the host is built on a subtle molecular biological basis. Their pathogenic effect characterized by mechanical, toxic, inoculating organism state of reactivity his organism, immunological allergic reorganization. It has been proved that species Dirofilaria immitis are most nematodes this genus because localization imaginal stage parasite causes more complex pathogenesis invasion. study aimed to establish changes in hematological parameters dogs infected with D. immitis, considering intensity microfilariasis Studies have shown invasion up 20 larvae/cm3 blood dogs, significant number erythrocytes, leukocytes, platelets, hemoglobin, hematocrit ESR were not found. 20–40 decreases erythrocytes 11.92 % (P < 0.05), hemoglobin content 16.33 12.70% 0.05) leukocytes increases 15.17 0.05). Indicators 40–60 showed blood, which decrease 25.54 0.001), platelets 34.03 0.01), 30.86 20.56 0.001) an increase 32.75 1.84 times 0.001). At indicators than 60 larvae/cm3, 47.21 %, thrombocytes 42.84 42.27 indicator 41.57 44.98 2.51 times. In leukoform increasing rates microfilariae invasion, eosinophils gradually 62.38 rod-shaped neutrophils 27.48 monocytes 23.21 0.01) lymphocytes reduced 45.45 data obtained indicate importance determining these for heartworm disease, complements picture clinical examination animals will allow effective treatment